Oscar R. Colegio, MD, PhD, is an Assistant Professor of Dermatology at Yale School of Medicine where his clinical practice and research is focused on immunodeficiency-associated skin cancers and skin disorders associated with solid organ transplantation. Under the guidance of his post-doctoral fellowship mentor Ruslan Medzhitov, PhD, he has and continues to characterize the role of immune cells called macrophages in tumor progression. The focus of these studies has been to identify pathways of tumorigenesis critical to a variety of murine tumor types including lung carcinoma, melanoma, colon carcinoma and cutaneous squamous cell carcinoma. Parallel studies in identifying tumor-promoting pathways induced by infiltrating macrophages in human squamous cell carcinomas from immunosuppressed vs non-immunosuppressed patients is the current focus of the lab.
During his postdoctoral studies, Dr. Colegio was selected to be a Howard Hughes Medical Institute Fellow and a Robert Black Fellow of the Damon Runyon Cancer Research Foundation. He is currently a Scholar of the Yale Center for Clinical Investigation and is supported by the Yale SPORE in Skin Cancer and the Dermatology Foundation.
Dr. Colegio is a member of several professional organizations related to his clinical and research interests. He is a member of the International Transplant Skin Cancer Collaborative, where he serves on the Board of Directors and is the Director of the Committee for Research, and the Society for Investigative Dermatology, where he serves on the Committee for Translational Research.