Jordt Lab Publications

Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE and Julius D (2007) The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448(7150):204-208.

Boehmerle W, Zhang K, Sivula M, Heidrich FM, Lee Y, Jordt SE and Ehrlich BE (2007) Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. PNAS 104(26):11103-11108.

Bautista DM*, Jordt SE*, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI and Julius D (2006) TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124(6):1269-1282.(*equally contributing authors) abstractarticle (.pdf)Cell perspective articleNature Reviews Neuroscience ArticlePress ReleaseNPR Story

Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Hogestatt ED, Julius D, Jordt SE and Zygmunt PM (2005) Pungent products from garlic activate the sensory ion channel TRPA1. PNAS 102(34):12248-12252. abstractarticle (.pdf)

Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Hogestatt ED, Meng ID and Julius D (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427(6971):260-265. abstractarticle (.pdf)

Jordt SE, McKemy DD and Julius D (2003) Lessons from peppers and peppermint: the molecular logic of thermosensation. Current Opinion in Neurobiology 13(4):487-492. abstractarticle (.pdf)

Jordt SE and Julius D (2002) Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108(3):421-430. abstractarticle (.pdf)

Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV and Julius D (2001) Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature 411(6840):957-962. abstractarticle (.pdf)

Jordt SE*, Tominaga M* and Julius D (2000) Acid potentiation of the capsaicin receptor determined by a key extracellular site. PNAS 97(14):8134-8139. (*equally contributing authors) abstractarticle (.pdf)

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Sven-Eric Jordt
Assistant Professor
Department of Pharmacology
Yale University School of Medicine
Office: (203) 785-2159
Lab: (203) 737-1560
©2005 Sven-Eric Jordt